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Table 1 LPS-stimulated gene expression differences between HuNOS2 -/- /mNos2 -/- and WT mice brain at 24 hrs post injection

From: The impact of human and mouse differences in NOS2 gene expression on the brain’s redox and immune environment

Gene abbreviation Gene name Significantly different
*Prdx3 Periredoxin 3 WT>HN
Prdx4 Periredoxin 4 WT>HN
Prdx5 Periredoxin 5 WT>HN
Gsr Glutathione reductase WT>HN
Cyba NADPH oxidase Cytochrome- b subunit a HN>WT
Cat Catalase WT>HN
Epx Eosinophil peroxidase HN>WT
Gpx4 Glutathione peroxidase 4 HN>WT
Nqo1 NAD(P)H dehydrogenase 1-Quinone 1 WT>HN
Gsr Glutathione reductase WT>HN
*Lpo lactoperoxidase HN>WT
Ireb2 Iron responsive element binding protein 2 WT>HN
RAD51 RAD51 recombinase HN>WT
*Recql4 REC-q like protein 4 (helicase) ND
Hbq1 Hemoglobin theta 1 WT>HN
*IL-22 Interleukin 22 HN>WT
Rag2 Recombination activating gene 2 WT>HN
Slc38a1 Solute Carrier 38a1 (glutamine transporter) WT>HN
  1. *Gene analysis was confirmed by additional RT-PCR (See Figure 4).