Table 2 Correlation between age, MMSE and biomarker levels in the entire CSF material ^a

Cont (N = 33)

   Age

N.S.

N.S.

N.S.

   MMSE

N.S.

N.S.

N.S.

   Aβ1-42

rho = 0.560, P = 0.001

rho = 0.468, P = 0.007

N.S.

   T-tau

rho = 0.564, P = 0.001

rho = 0.563, P = 0.001

rho = 0.656, P = 0.0001

   P-tau₁₈₁

rho = 0.735, P < 0.0001

rho = 0.715, P < 0.0001

rho = 0.659, P < 0.0001

   SNAP-25, Ac-2-16

-

rho = 0.859, P < 0.0001

rho = 0.718, P < 0.0001

   SNAP-25, 17-31

-

-

rho = 0.799, P < 0.0001

AD (N = 36)

   Age

N.S.

N.S.

N.S.

   MMSE

rho = -0.509, P = 0.002

N.S.

N.S.

   Aβ1-42

N.S.

N.S.

N.S.

   T-tau

rho = 0.557, P = 0.0004

rho = 0.732, P < 0.0001

rho = 0.824, P < 0.0001

   P-tau₁₈₁

rho = 0.717, P < 0.0001

rho = 0.808, P < 0.0001

rho = 0.835, P < 0.0001

   SNAP-25, Ac-2-16

-

rho = 0.836, P < 0.0001

rho = 0.720, P < 0.0001

   SNAP-25, 17-31

-

-

rho = 0.900, P < 0.0001