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Figure 6 | Molecular Neurodegeneration

Figure 6

From: Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury

Figure 6

Quantitative analysis of microglial response to rTBI. Bar graphs in the left column (A-D) indicate mean ± SD fractal dimension for microglial morphology in (A) olfactory nerve layer, (B) corpus callosum, (C) brachium of superior colliculus, and (D) optic tract. Bar graphs in the right column (E-H) show mean ± SD number of Iba-1 positive cells per mm2 in the same white matter regions. Data were analyzed by two-way ANOVA followed by a Tukey post-hoc test. Numbers inside the bars indicate sample size. For all graphs, * indicates a significant rTBI effect within a particular time point while # indicates a significant time effect within rTBI group. *: p < 0.05, **: p < 0.01, ***: p < 0.001, ****: p < 0.0001. ##: p < 0.01, ####: p < 0.0001.

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