Figure 9From: Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injuryCHIMERA device and mouse head positioning. (A) The picture depicts the CHIMERA device. Various parts are labeled with numbers as follows: 1. head plate, 2. body plate, 3. animal bed, 4. Velcro straps, 5. air tank, 6. air pressure regulator, 7. digital pressure gauge, 8. two-way solenoid valve, 9 vertical piston barrel. (B) Close-up view of animal strapped on the holding platform. (C) Location of impact relative to the mouse head and brain. P: impact piston. (D) Air pressure-energy calibration curve was obtained by driving a 50Â g piston at increasing air pressure values and calculating the resultant impact energy. The graph depicts three measurements for each air pressure value.Back to article page