| |
TP53 genotype
|
dominant model
|
recessive model
|
|---|
|
PI
|
0.002
|
0.73
|
0.01
|
|
MSSS
|
0.02
|
0.30
|
0.02
|
|
MV
|
0.04
|
0.16
|
0.03
|
|
RNFL thickness
|
0.01
|
0.02
|
0.005
|
- PI, progression index; MSSS, Multiple Sclerosis Severity Scale; MV, macular volume; RNFL, retinal nerve fiber layer. Although our sample was too small to test other statistical associations, higher values of both PI and MSSS were present in Arg/Arg carriers among patients with undetectable IL-1β (PI: Pro/Pro 0.16 +/- 0.13, Arg/Pro 0.14 +/- 0.09, Arg/Arg 0.21 +/- 0.17; MSSS: Pro/Pro 1.73 +/- 1.62, Arg/Pro 1.73 +/- 1.68, Arg/Arg 2.61 +/- 2.33).
