Figure 1From: The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammationAnalysis of spontaneous behaviour. Spontaneous behaviour of 2-month-old (A, B and C) and 4-month-old (D, E and F) NMRI male mice were exposed to 0, 0.02, 0.1, 0.5 or 1.0 Gy gamma radiation on postnatal day 10. The data were subjected to an ANOVA with split-plot design and significant treatment × time interactions were observed for 2-month-old and 4-month-old behaviour including locomotion, rearing, and total activity. Pairwise testing between control animals and animals exposed to gamma radiation was performed using Duncan’s MRT test. The statistical differences are indicated as: (A) significantly different vs. control, p ≤ 0.01; (a) significantly different vs. control, p ≤ 0.05; (B) significantly different vs. 0.02 Gy, p ≤ 0.01; (b) significantly different vs. 0.02 Gy, p ≤ 0.05; (C) significantly different vs. 0.1 Gy, p ≤ 0.01; (c) significantly different vs. 0.1 Gy, p ≤ 0.05; (D) significantly different vs. 0.5 Gy, p ≤ 0.01; (d) significantly different vs. 0.5 Gy, p ≤ 0.05; n = 12 per exposure group.Back to article page