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Figure 2 | Molecular Neurodegeneration

Figure 2

From: Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice

Figure 2

VL and immune profiles in HIV-1 infected humanized mice. (A) Flow cytometric analysis of CD4+ and CD8+ T cells in blood of HIV-1 infected mice (n = 10). The x-axis is the weeks following HIV-1 infection. (B) VL dynamics in plasma of replicate blood samples from A. Mice were bled once every 4 weeks starting from 2nd week post-infection. Mean ± SEM are shown in both A and B. (C) Total HIV-1gag RNA levels in the cortex was analyzed by real time RT-PCR. Data is expressed as HIV-1 RNA copies/μg total RNA after normalizing against GAPDH (used as an internal control). (D) For comparison, HIV-1 viral RNA in the peripheral blood at the end point is presented as viral RNA copies/ml.

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