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Figure 4 | Molecular Neurodegeneration

Figure 4

From: Structural biology of presenilin 1 complexes

Figure 4

Structure of presenilin protein homologue, SPP. (A) Crystallographic tetramer of MCMJR1 (PDB 4hyc). The image is generated by PyMOL and coloured to emphasize different domains. (B) Rainbow coloured (The PyMOL Molecular Graphics System, LLC) MCMJR1 monomer structure (PDB 4hyc, chain A). The active site (magenta) is buried within a hydrophilic pocket between TM domains.

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