Table 1 Two-way ANOVA of strain background and age effects on soluble and insoluble tau in 6.5 and 10.5Â month-old rTg4510 B6 mice compared to rTg4510 mice
From: Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model
| Â | Strain Background | Age | Interaction | |||
|---|---|---|---|---|---|---|
Fraction stain | F (DFn, DFd) | P value | F (DFn, DFd) | P value | F (DFn, DFd) | P value |
Soluble E1 1 | F (1, 10) = 3.60 | P = 0.09 | F (1, 10) = 3.20 | P = 0.10 | F (1, 10) = 0.94 | P = 0.36 |
Soluble Tau5 1 | F (1, 10) = 11.00 | P < 0.01 | F (1, 10) = 3.20 | P = 0.10 | F (1, 10) = 0.05 | P = 0.82 |
Soluble CP13 1 | F (1, 10) = 2.40 | P = 0.15 | F (1, 10) = 0.06 | P = 0.81 | F (1, 10) = 0.25 | P = 0.63 |
Soluble PHF1 1 | F (1, 10) = 20.00 | P < 0.01 | F (1, 10) = 4.80 | P = 0.05 | F (1, 10) = 0.57 | P = 0.47 |
Insoluble E1 | F (1, 10) = 3.90 | P = 0.08 | F (1, 10) = 0.002 | P = 0.97 | F (1, 10) = 0.002 | P = 0.97 |
Insoluble Tau5 | F (1, 10) = 2.70 | P = 0.13 | F (1, 10) = 1.20 | P = 0.29 | F (1, 10) = 0.50 | P = 0.50 |
Insoluble CP13 2 | F (1, 10) = 3.60 | P = 0.09 | F (1, 10) = 0.29 | P = 0.60 | F (1, 10) = 0.06 | P = 0.81 |
Insoluble PHF1 2 | F (1, 10) = 0.04 | P = 0.85 | F (1, 10) = 2.90 | P = 0.12 | F (1, 10) = 0.75 | P = 0.41 |