Figure 4From: Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model Effects of CD2AP on Aβ levels in 1-month old PS1APP mice. PS1APP/CD2AP+/+ (n = 12 total, 6 females and 6 males) and PS1APP/CD2AP−/− (n = 12 total, 7 females and 5 males) mice were sacrificed at 1-month of age. The cortices were homogenized in PBS. Aβ40 (A), Aβ42 (B) and Aβ42/ Aβ40 (C) ratio were measured. (**, p < 0.01, Student’s t-test).Back to article page