Figure 1From: Aβ-induced degradation of BMAL1 and CBP leads to circadian rhythm disruption in Alzheimer’s disease Disrupted circadian rhythm in 5XFAD mice. (A & B) Altered rhythmic waveform of home cage activity and body temperature in two-month-old 5XFAD mice in light–dark (LD) and dark-dark (DD) cycle. (C & D) Altered rhythmic waveform of home cage activity and body temperature in eight-month-old 5XFAD mice in LD and DD cycle.Back to article page