Table 1 ANOVA F and p values for BT and HCA rhythms
From: Aβ-induced degradation of BMAL1 and CBP leads to circadian rhythm disruption in Alzheimer’s disease
Physiological indices | Factors | |||
|---|---|---|---|---|
Circadian time | Genotype | Interaction | ||
Young LD | Home cage activity | F(24,576)=49.97; ****p<0.0001 | F(1,576)=0.58; n.s.p=0.4526 | F(24.576)=2.34; ****p<0.000l |
Body temperature | F(24,576)=14356; ****p<0.000l | F(1,576)=0.02; n.s.p=0.8802 | F(24,576)=311; ****p<0.0001 | |
Young DD | Home cage activity | F(23,276)=l3.77; ****p<0.0001 | F(1,275)=32.60: ****p<0.0001 | F(23,276)=l.57; n.s.p=0051 |
Body temperature | F(24,288)=47.07; ****p<0.0001 | F(1,288).67.53; ****p<0.0001 | F(24,288)=3.42; ****p<0.0001 | |
Old LD | Home cage activity | F(24.528)=101.23; ****p<0.000 | F(1.528)=1818.65; ****p<0.000l | F(24.528)=30.03; ****p<0.0001 |
Body temperature | F(24.528=143.35; ****p<0.0001 | F(1,528)=40.62; ****p<0.0001 | F(24.528)4.34; ****p<0.0001 | |
Old DD | Home cage activity | F(24.288)=14.88; ****p<0.0001 | F(1.288)=13.82; **p=0.00029 | F(24.288)=4.56; ****p<0.0001 |
Body temperature | F(24.288)=57.73; ****p<0.0001 | F(l,288)=133.24; ****p<0.0001 | F(24.288)=6.02; ****p<0.0001 | |