Figure 4From: Lazarillo-related Lipocalins confer long-term protection against type I Spinocerebellar Ataxia degeneration contributing to optimize selective autophagy Effects of GLaz over-expression on cell death due to hATXN1 82Q -dependent degeneration, and on SCA1-modifiers expression. A, TUNEL analysis of apoptotic cell death in paraffin sections of degenerated (gmrā>āhATXN182Q) and GLaz rescued (gmrā>āhATXN182Qā+āGLaz2) retinas. Representative examples of retina sections showing a decreased number of apoptotic nuclei (white arrows) in flies that over-express GLaz. B, hATXN1 mRNA levels in fly heads of the SCA1 model and lines expressing a double dose of GLaz. C, RT-qPCR expression levels of the SCA1 neurodegeneration modifiers GstS1 and Vib. Statistical differences of RT-qPCR data were assayed by MannāWhitney U-test. *Pā<ā0.05.Back to article page