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Figure 1 | Molecular Neurodegeneration

Figure 1

From: Selective loss of glucocerebrosidase activity in sporadic Parkinson’s disease and dementia with Lewy bodies

Figure 1

Lysosomal enzyme activities in human brain. a) Cluster analysis of lysosomal enzyme activities. Lysosomal specific activities were normalized with respect to their means and standard deviations, while patients were summarized using their respective diagnostic group; b) Boxplots of the GCase specific activity across different brain areas. In the table below the figure, the significant comparisons are reported according to the statistical model used; c) mRNA levels of GBA gene. 2-ΔCT values normalized by housekeeping genes GAPDH and SDHA. *p < 0.05 using Wilcoxon two groups test and nonparametric ANCOVA model with adjustment for post mortem delay.

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Molecular Neurodegeneration

ISSN: 1750-1326