Figure 7
From: Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathology
Age-dependent change of CSF total tau in rTg4510 mice. CSF total tau was measured using an AlphaLISA assay with biotin HT7 antibody for capture and antibody BT2 conjugated acceptor beads for detection. One microliter of CSF was used per assay and recombinant tau (Milipore) was used to generate a standard curve for quantification. A. Age-dependent change in CSF total tau in Tg4510 mice. B. Re-plotting of age-dependent changes in mean brain PHF6 tau levels from Figure 3A (open circle) and mean CSF tau levels from Figure 7A (solid circle). Error bars represent the standard error of the mean.