Table 1 List of tau species detected and antibody reagents used in the AlphaLISA immunoassays developed for this study
From: Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathology
Tau Species | Biotin-donor | Acceptor |
|---|---|---|
Total tau | Tau12 | HT7 |
Tau aggregates | HT7 | HT7 |
p231 | HT7 | PHF6 |
pT202/205 | HT7 | AT8 |
Global p-tau | HT7 | anti-pThr |
pT231 | HT7 | AT180 |
pT181 | HT7 | AT270 |
pS212/T214 | HT7 | AT100 |
pS262 | HT7 | pS262 |
pT396 | HT7 | PHF13 |
pS400 | HT7 | pS400 |
pS404 | HT7 | pS404 |
pS409 | HT7 | pS409 |
pS412 | HT7 | pS412 |
Ac-Lys280 | HT7 | Anti-Ac-Lys280 |
Ac-tau | HT7 | anti-acetyl-Lys |
pY-tau | HT7 | anti-p-tyrosine |
ub-tau | HT7 | anti-ubiquitin |
nY29 tau | HT7 | anti-nY29 |
CSF total tau | HT7 | BT2 |