Table 2 Demographic information of studied African Americans
From: TREM2 is associated with increased risk for Alzheimer’s disease in African Americans
Cohort | No. of participants | Type | Sequencing/Genotyping strategy | Cases | Controls | ||
|---|---|---|---|---|---|---|---|
N | Range of age at onset/diagnosis | N | Range of age at last assessment | ||||
Knight-ADRC + NIA-LOAD | 338 | Clinical | Pooled sequencing/Sequenom + KASPar | 202 | 60-94 | 136 | 60-97 |
Mayo Clinic | 513 | Clinical | Sanger sequencing (exons 1–5 in AD cases and exon 2 in controls)/Taqman + KASPar | 179 | 61-99 | 334 | 60-98 |
Indiana University | 1,321 | Clinical | Sequenom + KASPar | 149 | 72-102 | 1,172 | 70-102 |
WHICAP | 1,024 | Clinical | KASPar | 246 | 68-101 | 778 | 66-99 |
Emory University | 197 | Clinical | Taqman + KASPar | 130 | 61-98 | 67 | 60-94* |