Figure 7
From: Making (anti-) sense out of huntingtin levels in Huntington disease
HTT antisense expression in HD patient-derived fibroblasts and brain tissue. Gel electrophoresis of HTTAS amplified using strand- and HTTAS isoform-specific primers. (A) RT-PCR of patient-derived fibroblasts from a control (GM04204), an HD patient (GM02173), an HD patient homozygous for the CAG repeat expansion (GM04857) and a juvenile HD patient (GM05539). (B) RT-PCR of post-mortem brain tissue from a control (H121), an HD patient (HC105), and 2 juvenile HD patients (HD192 and HD86). Allelic CAG repeat sizes below each lane.