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Fig. 6 | Molecular Neurodegeneration

Fig. 6

From: Brca1 is expressed in human microglia and is dysregulated in human and animal model of ALS

Fig. 6

Up-regulation of microglial Brca1 expression in human ALS spinal cords. Brightfield micrographs displaying Brca1 expression within the spinal cords of control (a & c) and ALS cases (b & d). Bar graphs showing the increase in Brca1 intensity within the white (e) and grey (f) matters of the spinal cord in ALS compared to control cases. Bars represent mean ± SEM (n = 5 for ALS and 14 for controls). *p < 0.05. Scale bar (ad): 100 μm

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