TY - JOUR AU - Harold, D. AU - Abraham, R. AU - Hollingworth, P. AU - Sims, R. AU - Gerrish, A. AU - Hamshere, M. L. PY - 2009 DA - 2009// TI - Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease JO - Nat Genet VL - 41 UR - https://doi.org/10.1038/ng.440 DO - 10.1038/ng.440 ID - Harold2009 ER - TY - JOUR AU - Lambert, J. C. AU - Heath, S. AU - Even, G. AU - Campion, D. AU - Sleegers, K. AU - Hiltunen, M. PY - 2009 DA - 2009// TI - Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease JO - Nat Genet VL - 41 UR - https://doi.org/10.1038/ng.439 DO - 10.1038/ng.439 ID - Lambert2009 ER - TY - JOUR AU - Bettens, K. AU - Brouwers, N. AU - Engelborghs, S. AU - Lambert, J. -. C. AU - Rogaeva, E. AU - Vandenberghe, R. PY - 2012 DA - 2012// TI - Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk JO - Mol Neurodegener VL - 7 UR - https://doi.org/10.1186/1750-1326-7-3 DO - 10.1186/1750-1326-7-3 ID - Bettens2012 ER - TY - JOUR AU - Ng, P. C. AU - Henikoff, S. PY - 2003 DA - 2003// TI - SIFT: predicting amino acid changes that affect protein function JO - Nucleic Acids Res VL - 31 UR - https://doi.org/10.1093/nar/gkg509 DO - 10.1093/nar/gkg509 ID - Ng2003 ER - TY - JOUR AU - Adzhubei, I. A. AU - Schmidt, S. AU - Peshkin, L. AU - Ramensky, V. E. AU - Gerasimova, A. AU - Bork, P. PY - 2010 DA - 2010// TI - A method and server for predicting damaging missense mutations JO - Nat Methods VL - 7 UR - https://doi.org/10.1038/nmeth0410-248 DO - 10.1038/nmeth0410-248 ID - Adzhubei2010 ER - TY - JOUR AU - Nuutinen, T. AU - Suuronen, T. AU - Kauppinen, A. AU - Salminen, A. PY - 2009 DA - 2009// TI - Clusterin: a forgotten player in Alzheimer's disease JO - Brain Res Rev VL - 61 UR - https://doi.org/10.1016/j.brainresrev.2009.05.007 DO - 10.1016/j.brainresrev.2009.05.007 ID - Nuutinen2009 ER - TY - JOUR AU - Pasinetti, G. M. AU - Johnson, S. A. AU - Oda, T. AU - Rozovsky, I. AU - Finch, C. E. PY - 1994 DA - 1994// TI - Clusterin (SGP-2): a multifunctional glycoprotein with regional expression in astrocytes and neurons of the adult rat brain JO - J Comp Neurol VL - 339 UR - https://doi.org/10.1002/cne.903390307 DO - 10.1002/cne.903390307 ID - Pasinetti1994 ER - TY - JOUR AU - Saura, J. AU - Petegnief, V. AU - Wu, X. AU - Liang, Y. AU - Paul, S. M. PY - 2003 DA - 2003// TI - Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro: opposite effects of lipopolysaccharide JO - J Neurochem VL - 85 UR - https://doi.org/10.1046/j.1471-4159.2003.01788.x DO - 10.1046/j.1471-4159.2003.01788.x ID - Saura2003 ER - TY - JOUR AU - Criswell, T. AU - Beman, M. AU - Araki, S. AU - Leskov, K. AU - Cataldo, E. AU - Mayo, L. D. PY - 2005 DA - 2005// TI - Delayed activation of insulin-like growth factor-1 receptor/Src/MAPK/Egr-1 signaling regulates clusterin expression, a pro-survival factor JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.M412569200 DO - 10.1074/jbc.M412569200 ID - Criswell2005 ER - TY - JOUR AU - Ling, I. F. AU - Bhongsatiern, J. AU - Simpson, J. F. AU - Fardo, D. W. AU - Estus, S. PY - 2012 DA - 2012// TI - Genetics of clusterin isoform expression and Alzheimer's disease risk JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0033923 DO - 10.1371/journal.pone.0033923 ID - Ling2012 ER - TY - JOUR AU - Kimura, K. AU - Yamamoto, M. PY - 1996 DA - 1996// TI - Modification of the alternative splicing process of testosterone-repressed prostate message-2 (TRPM-2) gene by protein synthesis inhibitors and heat shock treatment JO - Biochim Biophys Acta VL - 1307 UR - https://doi.org/10.1016/0167-4781(96)00017-6 DO - 10.1016/0167-4781(96)00017-6 ID - Kimura1996 ER - TY - JOUR AU - Leskov, K. S. AU - Klokov, D. Y. AU - Li, J. AU - Kinsella, T. J. AU - Boothman, D. A. PY - 2003 DA - 2003// TI - Synthesis and functional analyses of nuclear clusterin, a cell death protein JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.M209233200 DO - 10.1074/jbc.M209233200 ID - Leskov2003 ER - TY - JOUR AU - Prochnow, H. AU - Gollan, R. AU - Rohne, P. AU - Hassemer, M. AU - Koch-Brandt, C. AU - Baiersdorfer, M. PY - 2013 DA - 2013// TI - Non-secreted clusterin isoforms are translated in rare amounts from distinct human mRNA variants and do not affect Bax-mediated apoptosis or the NF-kappaB signaling pathway JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0075303 DO - 10.1371/journal.pone.0075303 ID - Prochnow2013 ER - TY - JOUR AU - Lambert, J. C. AU - Ibrahim-Verbaas, C. A. AU - Harold, D. AU - Naj, A. C. AU - Sims, R. AU - Bellenguez, C. PY - 2013 DA - 2013// TI - Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JO - Nat Genet VL - 45 UR - https://doi.org/10.1038/ng.2802 DO - 10.1038/ng.2802 ID - Lambert2013 ER - TY - JOUR AU - Narayan, P. AU - Orte, A. AU - Clarke, R. W. AU - Bolognesi, B. AU - Hook, S. AU - Ganzinger, K. A. PY - 2011 DA - 2011// TI - The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-beta(1–40) peptide JO - Nat Struct Mol Biol VL - 19 UR - https://doi.org/10.1038/nsmb.2191 DO - 10.1038/nsmb.2191 ID - Narayan2011 ER - TY - JOUR AU - Rosenberg, M. E. AU - Silkensen, J. PY - 1995 DA - 1995// TI - Clusterin: physiologic and pathophysiologic considerations JO - Int J Biochem Cell Biol VL - 27 UR - https://doi.org/10.1016/1357-2725(95)00027-M DO - 10.1016/1357-2725(95)00027-M ID - Rosenberg1995 ER - TY - JOUR AU - Thambisetty, M. AU - An, Y. AU - Kinsey, A. AU - Koka, D. AU - Saleem, M. AU - Guntert, A. PY - 2012 DA - 2012// TI - Plasma clusterin concentration is associated with longitudinal brain atrophy in mild cognitive impairment JO - Neuroimage VL - 59 UR - https://doi.org/10.1016/j.neuroimage.2011.07.056 DO - 10.1016/j.neuroimage.2011.07.056 ID - Thambisetty2012 ER - TY - JOUR AU - Dabbs, R. A. AU - Wilson, M. R. PY - 2014 DA - 2014// TI - Expression and purification of chaperone-active recombinant clusterin JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0086989 DO - 10.1371/journal.pone.0086989 ID - Dabbs2014 ER - TY - JOUR AU - Zhou, Y. AU - Hayashi, I. AU - Wong, J. AU - Tugusheva, K. AU - Renger, J. J. AU - Zerbinatti, C. PY - 2014 DA - 2014// TI - Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein tau in Alzheimer's disease JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0103187 DO - 10.1371/journal.pone.0103187 ID - Zhou2014 ER - TY - JOUR AU - Engelborghs, S. AU - Dermaut, B. AU - Goeman, J. AU - Saerens, J. AU - Marien, P. AU - Pickut, B. A. PY - 2003 DA - 2003// TI - Prospective Belgian study of neurodegenerative and vascular dementia: APOE genotype effects JO - J Neurol Neurosurg Psychiatry VL - 74 UR - https://doi.org/10.1136/jnnp.74.8.1148 DO - 10.1136/jnnp.74.8.1148 ID - Engelborghs2003 ER - TY - JOUR AU - Engelborghs, S. AU - Dermaut, B. AU - Marien, P. AU - Symons, A. AU - Vloeberghs, E. AU - Maertens, K. PY - 2006 DA - 2006// TI - Dose dependent effect of APOE epsilon4 on behavioral symptoms in frontal lobe dementia JO - Neurobiol Aging VL - 27 UR - https://doi.org/10.1016/j.neurobiolaging.2005.02.005 DO - 10.1016/j.neurobiolaging.2005.02.005 ID - Engelborghs2006 ER - TY - JOUR AU - Bettens, K. AU - Brouwers, N. AU - Miegroet, H. AU - Gil, A. AU - Engelborghs, S. AU - Deyn, P. P. PY - 2009 DA - 2009// TI - Follow-Up study of susceptibility loci for Alzheimer's disease and onset Age identified by genome-wide association JO - J Alzheimers Dis VL - 19 ID - Bettens2009 ER - TY - STD TI - Reumers J, De Rijk P, Zhao H, Liekens A, Smeets D, Cleary J, et al. Optimized filtering reduces the error rate in detecting genomic variants by short-read sequencing. Nat Biotechnol. 2011. ID - ref23 ER - TY - JOUR AU - Li, H. AU - Durbin, R. PY - 2010 DA - 2010// TI - Fast and accurate long-read alignment with Burrows-Wheeler transform JO - Bioinformatics VL - 26 UR - https://doi.org/10.1093/bioinformatics/btp698 DO - 10.1093/bioinformatics/btp698 ID - Li2010 ER - TY - JOUR AU - McKenna, A. AU - Hanna, M. AU - Banks, E. AU - Sivachenko, A. AU - Cibulskis, K. AU - Kernytsky, A. PY - 2010 DA - 2010// TI - The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data JO - Genome Res VL - 20 UR - https://doi.org/10.1101/gr.107524.110 DO - 10.1101/gr.107524.110 ID - McKenna2010 ER - TY - JOUR AU - Abecasis, G. R. AU - Altshuler, D. AU - Auton, A. AU - Brooks, L. D. AU - Durbin, R. M. AU - Gibbs, R. A. PY - 2010 DA - 2010// TI - A map of human genome variation from population-scale sequencing JO - Nature VL - 467 UR - https://doi.org/10.1038/nature09534 DO - 10.1038/nature09534 ID - Abecasis2010 ER - TY - JOUR AU - Ferrer-Costa, C. AU - Gelpi, J. L. AU - Zamakola, L. AU - Parraga, I. AU - Cruz, X. AU - Orozco, M. PY - 2005 DA - 2005// TI - PMUT: a web-based tool for the annotation of pathological mutations on proteins JO - Bioinformatics VL - 21 UR - https://doi.org/10.1093/bioinformatics/bti486 DO - 10.1093/bioinformatics/bti486 ID - Ferrer-Costa2005 ER - TY - JOUR AU - Salmon, P. AU - Trono, D. PY - 2006 DA - 2006// TI - Production and titration of lentiviral vectors JO - Curr Protoc Neurosci VL - 4 ID - Salmon2006 ER - TY - JOUR AU - Schneider, C. A. AU - Rasband, W. S. AU - Eliceiri, K. W. PY - 2012 DA - 2012// TI - NIH Image to ImageJ: 25 years of image analysis JO - Nat Methods VL - 9 UR - https://doi.org/10.1038/nmeth.2089 DO - 10.1038/nmeth.2089 ID - Schneider2012 ER -