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Fig. 7 | Molecular Neurodegeneration

Fig. 7

From: Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice

Fig. 7

Mutant ubiquilin-2 expression induces ThioS-positive inclusions. Photos show Thioflavin-S staining that colocalizes (arrows; yellow in merged images) with intracellular ubiquilin-2-positive inclusions seen in mice injected with rAAV expressing mutant but not WT ubiquilin-2. Images shown are from mice aged 6 months, but similar findings were seen also in younger mice. (bar = 50 μm)

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