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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice

Fig. 5

Astrogliosis and αS inclusions within astrocytes, in M83 αS Tg mice injected with αS fibrils. a Percentage of GFAP-positive astrocytes per field area in the hippocampus (left) and entorhinal cortex (right) of M83 αS Tg mice stereotaxically injected with αS or cation exchanged αS fibrils or LPS in the hippocampus, versus PBS injected mice. P-values were determined by one-way ANOVA analyses. b Representative images of the hippocampus, showing double immunofluorescent staining with pSer129/81A (αS phosphorylated at Ser129) and GFAP. Individual images were overlaid (Merge) to show colocalization. Scale bar = 50 μm

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Molecular Neurodegeneration

ISSN: 1750-1326