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Fig. 6 | Molecular Neurodegeneration

Fig. 6

From: Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice

Fig. 6

Immunohistochemical analysis showing ependymal cell αS pathology in M83 αS Tg mice injected with αS fibrils. Representative immunohistochemical images of hemizygous M83 αS Tg mice injected with αS fibrils (a) or cation exchanged αS fibrils (b), and homozygous M83 αS Tg mice injected with PBS (c), or aged until motor impairments were observed (d). Images showing midline (left; below showing higher magnification) and lateral ventricle (right) stained with antibodies to αS phosphorylated at Ser129 (pSer129/81A), αS (Syn506) and a general inclusion marker (p62). Scale bars = 100 μm

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