From: A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice
Blood
Brain
Cmax (1 h, μM)
1.62
4.01
AUC 0-24 h (μM•h)
10.2
23.6
unbound AUC 0-24 h (μM•h)
0.63
0.54