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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: STIM2 protects hippocampal mushroom spines from amyloid synaptotoxicity

Fig. 3

STIM2 and pCaMKII are downregulated in hippocampal cultures treated with amyloid. a The expression levels of STIM2, STIM1, pCaMKII, and CaMKII were analyzed by Western blotting of lysates from WT hippocampal cultures exposed to Aβ40, Aβ42 or vehicle (Ctrl). Actin was used as a loading control. b Quantification of STIM2, STIM1, pCaMKII and CaMKII expression levels in WT cultures exposed to Aβ40, Aβ42 or vehicle (Ctrl) (normalized to actin levels). Graph represents the data from three independent experiments. Values are shown as mean ± SEM. *: p < 0.05 by ANOVA one-way and post hoc tests, n.s. (non specific)

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