Construct | Condition | Region | Genotype | Mice (n) | Cells (n) | Mean ± s.e.m (based on cell number) of normalized intensity values | Student’s t test | ||
p values (B6 vs. APP) | |||||||||
EGFP-htau | untreated | CA1 | B6 | 3 | 5 | 1.061±0.099 | p = 0.6210 | ||
EGFP-htau | untreated | CA1 | APPSDL | 5 | 5 | 1.111±0.120 | |||
Construct | Condition | Region | Genotype | Mice (n) | Cells (n) | Mean ± s.e.m (based on cell number) of normalized intensity values | One way ANOVA (together with EGFP-htau untreated, both genotypes) | p values (B6 vs. APP) | p values (vs. untreated same genotype) |
EGFP-htau | DAPT | CA1 | B6 | 3 | 6 | 0.827±0.066 | F (3,17) = 2.183 ; p = 0.1275 | p = 0.0273 | p = 0.2007 |
EGFP-htau | DAPT | CA1 | APPSDL | 4 | 5 | 1.197±0.154 | p = 0.5981 | ||
EGFP-htau | EpoD | CA1 | B6 | 4 | 5 | 1.119±0.138 | F (3,16) = 0.2108 ; p = 0.8874 | p = 0.8533 | p = 0.5763 |
EGFP-htau | EpoD | CA1 | APPSDL | 5 | 5 | 1.148±0.066 | p = 0.8135 | ||
EGFP-htau | CPP | CA1 | B6 | 5 | 5 | 0.945±0.176 | F (3,16) = 1.334 ; p = 0.2984 | p = 0.3752 | p = 0.6129 |
EGFP-htau | CPP | CA1 | APPSDL | 4 | 5 | 0.793±0.019 | p = 0.0745 | ||
EGFP-Ala htau | untreated | CA1 | B6 | 5 | 5 | 1.083±0.135 | F (3,16) = 0.6240 ; p = 0.6098 | p = 0.2952 | p = 0.7390 |
EGFP-Ala htau | untreated | CA1 | APPSDL | 5 | 5 | 0.917±0.068 | p = 0.2240 | ||
EGFP-PHP htau | untreated | CA1 | B6 | 3 | 5 | 1.174±0.064 | F (3,16) = 0.5229 ; p = 0.6727 | p = 0.9881 | p = 0.2937 |
EGFP-PHP htau | untreated | CA1 | APPSDL | 3 | 5 | 1.172±0.080 | p = 0.6495 |