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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway

Fig. 3

Statin-mediated IDE secretion from astrocytes is regulated by autophagic flux. a Lysosomal activity as determined with LysoTracker probe. Scale bar represents 10 μm. b Change in secreted IDE levels by inhibiting lysosome with bafilomycin. c & d Quantitative analysis of Fig. 3b (N = 3 experiments). Baf, bafilomycin. ** p < 0.01, # p < 0.05 vs. vehicle-treated cells

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