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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway

Fig. 5

Statin-induced AMPK activation is mediated by LKB1 in astrocytes. a Increased phosphorylation of LKB1 by treatment with simvastatin. b Statin-induced autophagy activation and IDE secretion levels in CaMKKβ or LKB1 knock-downed cells. c & d Quantitative analysis of Fig. 5b (N = 3 experiments). * p < 0.05, ** p < 0.01 vs. vehicle-treated cells. n.s. indicates no significant difference

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