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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice

Fig. 1

L-methionine treatment increases tau phosphorylation in the hippocampus. a Different phosphorylation epitopes of tau were evaluated in control and L-methionine hippocampal lysates. Each lane represents samples from a different animal. The quantification is shown in the right panel. b Immunocytochemistry was used to evaluate the presence of T231-positive cells. (Top left) Cortex and hippocampal sections of control mice; (top right) L-methionine sections at 20x (inset 40x). The diagram below showsthat the respective quantification (n ≥ 4) bars are mean ± SEM. *P < 0.05; **P < 0.01, ***P < 0.001

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Molecular Neurodegeneration

ISSN: 1750-1326