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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice

Fig. 3

Increased astrogliosis in animals chronically treated with L-methionine. a Western blot measurements of GFAP and Cd11b in hippocampal lysates from L-methionine and control mice. b Densitometric analysis of a). c Histological slices were analyzed for glial fibrillar acid protein (GFAP) and observed under microscopy in the CA1 area of the hippocampus. Upper images show three different magnifications (10x, 20x and 40x) of control zones. Lower images show comparable zones of L-methionine-treated mice. d Quantification of the photographs. e The soma area of GFAP was calculated against total area of field (n ≥ 4) Bars are mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Neurodegeneration

ISSN: 1750-1326