Skip to main content
Fig. 6 | Molecular Neurodegeneration

Fig. 6

From: LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate

Fig. 6

Phosphorylated NSF exhibits increased rate of SNARE complex disassembling in vitro. a Representative coomassie gels (CBB, coomassie brilliant blue) of SNARE complex incubated for increasing time with NSF phosphorylated or not by LRRK2-G2019S970–2527 in the presence of the co-factor alpha-SNAP. b Quantification of n = 3 independent experiments. Time points are relative to t = 0 which was set at 100 % (two-way ANOVA with Bonferroni’s post-test, ***p < 0.001)

Back to article page

Molecular Neurodegeneration

ISSN: 1750-1326