TY - JOUR AU - Alves da Costa, C. PY - 2003 DA - 2003// JO - Curr Mol Med VL - 3 UR - https://doi.org/10.2174/1566524033361690 DO - 10.2174/1566524033361690 ID - Alves da Costa2003 ER - TY - JOUR AU - Dev, K. K. AU - Hofele, K. AU - Barbieri, S. AU - Buchman, V. L. AU - Putten, H. PY - 2003 DA - 2003// TI - Part II: alpha-synuclein and its molecular pathophysiological role in neurodegenerative disease JO - Neuropharmacology VL - 45 UR - https://doi.org/10.1016/S0028-3908(03)00140-0 DO - 10.1016/S0028-3908(03)00140-0 ID - Dev2003 ER - TY - JOUR AU - Spillantini, M. G. AU - Crowther, R. A. AU - Jakes, R. AU - Hasegawa, M. AU - Goedert, M. PY - 1998 DA - 1998// TI - α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies JO - Proc Natl Acad Sci U S A VL - 95 UR - https://doi.org/10.1073/pnas.95.11.6469 DO - 10.1073/pnas.95.11.6469 ID - Spillantini1998 ER - TY - JOUR AU - Alves da Costa, C. AU - Ancolio, K. AU - Checler, F. PY - 2000 DA - 2000// TI - Wild-type but not Parkinson’s disease-related Ala53Thr-α-synuclein protect neuronal cells from apoptotic stimuli JO - J Biol Chem VL - 275 UR - https://doi.org/10.1074/jbc.M002413200 DO - 10.1074/jbc.M002413200 ID - Alves da Costa2000 ER - TY - JOUR AU - Alves da Costa, C. AU - Paitel, E. AU - Vincent, B. AU - Checler, F. PY - 2002 DA - 2002// TI - Alpha-synuclein lowers p53-dependent apoptotic response of neuronal cells. Abolishment by 6-hydroxydopamine and implication for Parkinson’s disease JO - J Biol Chem VL - 277 UR - https://doi.org/10.1074/jbc.M207825200 DO - 10.1074/jbc.M207825200 ID - Alves da Costa2002 ER - TY - JOUR AU - Alves da Costa, C. AU - Dunys, J. AU - Brau, F. AU - Wilk, S. AU - Cappai, R. AU - Checler, F. PY - 2006 DA - 2006// TI - 6-Hydroxydopamine but not 1-methyl-4-phenylpyridinium abolishes alpha-synuclein anti-apoptotic phenotype by inhibiting its proteasomal degradation and by promoting its aggregation JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M513903200 DO - 10.1074/jbc.M513903200 ID - Alves da Costa2006 ER - TY - JOUR AU - Costa, C. AU - Sunyach, C. AU - Giaime, E. AU - West, A. AU - Corti, O. AU - Brice, A. PY - 2009 DA - 2009// TI - Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson’s disease JO - Nat Cell Biol VL - 11 UR - https://doi.org/10.1038/ncb1981 DO - 10.1038/ncb1981 ID - Costa2009 ER - TY - JOUR AU - Sunico, C. AU - Nakamura, T. AU - Rockenstein, E. AU - Mante, M. AU - Adame, A. AU - Chan, S. PY - 2013 DA - 2013// TI - S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson’s disease JO - Mol Neurodegener VL - 8 UR - https://doi.org/10.1186/1750-1326-8-29 DO - 10.1186/1750-1326-8-29 ID - Sunico2013 ER - TY - JOUR AU - Zhang, C. AU - Lin, M. AU - Wu, R. AU - Wang, X. AU - Yang, B. AU - Levine, A. PY - 2011 DA - 2011// TI - Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect JO - Proc Natl Acad Sci U S A VL - 108 UR - https://doi.org/10.1073/pnas.1113884108 DO - 10.1073/pnas.1113884108 ID - Zhang2011 ER - TY - JOUR AU - Giaime, E. AU - Sunyach, C. AU - Druon, C. AU - Scarzello, S. AU - Robert, G. AU - Grosso, S. PY - 2010 DA - 2010// TI - Loss of function of DJ-1 triggered by Parkinson’s disease-associated mutation is due to proteolytic resistance to caspase-6 JO - Cell Death Diff VL - 17 UR - https://doi.org/10.1038/cdd.2009.116 DO - 10.1038/cdd.2009.116 ID - Giaime2010 ER - TY - JOUR AU - Duplan, E. AU - Giaime, E. AU - Viotti, J. AU - Sevalle, J. AU - Corti, O. AU - Brice, A. PY - 2013 DA - 2013// TI - ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1 JO - J Cell Sci VL - 126 UR - https://doi.org/10.1242/jcs.127340 DO - 10.1242/jcs.127340 ID - Duplan2013 ER - TY - JOUR AU - Freedman, D. A. AU - Levine, A. J. PY - 1998 DA - 1998// TI - Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6 JO - Mol Cell Biol VL - 18 UR - https://doi.org/10.1128/MCB.18.12.7288 DO - 10.1128/MCB.18.12.7288 ID - Freedman1998 ER - TY - JOUR AU - Kamijo, T. AU - Zindy, F. AU - Roussel, M. F. AU - Quelle, D. E. AU - Downing, J. R. AU - Ashmun, R. A. PY - 1997 DA - 1997// TI - Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF JO - Cell VL - 91 UR - https://doi.org/10.1016/S0092-8674(00)80452-3 DO - 10.1016/S0092-8674(00)80452-3 ID - Kamijo1997 ER - TY - JOUR AU - Brosh, R. AU - Rotter, V. PY - 2009 DA - 2009// TI - When mutants gain new powers: news from the mutant p53 field JO - Nat Rev Cancer VL - 9 ID - Brosh2009 ER - TY - JOUR AU - Goh, A. M. AU - Coffill, C. R. AU - Lane, D. P. PY - 2011 DA - 2011// TI - The role of mutant p53 in human cancer JO - J Pathol VL - 223 UR - https://doi.org/10.1002/path.2784 DO - 10.1002/path.2784 ID - Goh2011 ER - TY - JOUR AU - El-Deiry, W. S. AU - Kern, S. E. AU - Pietenpol, J. A. AU - Kinzler, K. W. AU - Vogelstein, B. PY - 1992 DA - 1992// TI - Definition of a consensus binding site for p53 JO - Nat Genet VL - 1 UR - https://doi.org/10.1038/ng0492-45 DO - 10.1038/ng0492-45 ID - El-Deiry1992 ER - TY - JOUR AU - Vousden, K. H. PY - 2000 DA - 2000// TI - p53: death star JO - Cell VL - 103 UR - https://doi.org/10.1016/S0092-8674(00)00171-9 DO - 10.1016/S0092-8674(00)00171-9 ID - Vousden2000 ER - TY - JOUR AU - Vousden, K. H. AU - Lu, X. PY - 2002 DA - 2002// TI - Live or let die: the cell’s response to p53 JO - Nat Rev Cancer VL - 2 UR - https://doi.org/10.1038/nrc864 DO - 10.1038/nrc864 ID - Vousden2002 ER - TY - JOUR AU - Checler, F. PY - 2014 DA - 2014// TI - Alves da Costa C. p53 in neurodegenerative diseases and brain cancers JO - Pharmacol Ther VL - 142 UR - https://doi.org/10.1016/j.pharmthera.2013.11.009 DO - 10.1016/j.pharmthera.2013.11.009 ID - Checler2014 ER - TY - JOUR AU - Alves da Costa, C. AU - Checler, F. PY - 2011 DA - 2011// TI - Apoptosis in Parkinson’s disease: is p53 the missing link between genetic and sporadic Parkinsonism? JO - Cell Signal VL - 23 UR - https://doi.org/10.1016/j.cellsig.2010.10.020 DO - 10.1016/j.cellsig.2010.10.020 ID - Alves da Costa2011 ER - TY - JOUR AU - Vila, M. AU - Vukosavic, S. AU - Jackson-Lewis, V. AU - Neystat, M. AU - Jakowec, M. AU - Przedborski, S. PY - 2000 DA - 2000// TI - α-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the Parkinsonian toxin MPTP JO - J Neurochem VL - 74 UR - https://doi.org/10.1046/j.1471-4159.2000.740721.x DO - 10.1046/j.1471-4159.2000.740721.x ID - Vila2000 ER - TY - JOUR AU - Grundemann, J. AU - Schlaudraff, F. AU - Haeckel, O. AU - Liss, B. PY - 2008 DA - 2008// TI - Elevated alpha-synuclein mRNA levels in individual UV-laser-microdissected dopaminergic substantia nigra neurons in idiopathic Parkinson’s disease JO - Nucleic Acids Res VL - 36 UR - https://doi.org/10.1093/nar/gkn084 DO - 10.1093/nar/gkn084 ID - Grundemann2008 ER - TY - JOUR AU - Essletzbichler, P. AU - Konopka, T. AU - Santoro, F. AU - Chen, D. AU - Gapp, B. V. AU - Kralovics, R. PY - 2014 DA - 2014// TI - Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line JO - Genome Res VL - 24 UR - https://doi.org/10.1101/gr.177220.114 DO - 10.1101/gr.177220.114 ID - Essletzbichler2014 ER - TY - JOUR AU - Viotti, J. AU - Duplan, E. AU - Caillava, C. AU - Condat, J. AU - Goiran, T. AU - Giordano, C. PY - 2014 DA - 2014// TI - Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity JO - Oncogene VL - 33 UR - https://doi.org/10.1038/onc.2013.124 DO - 10.1038/onc.2013.124 ID - Viotti2014 ER -