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Table 2 Top ten biological clusters associated with transcripts dysregulated in at least 3 out of 4 conditions: misexpression in the hippocampus and/or cortex of transgenic and/or wild type mice

From: Vitamin D interacts with Esr1 and Igf1 to regulate molecular pathways relevant to Alzheimer’s disease

Annotation term

Number of genes

Genes

Hormone activity

8

Avp, Igf1, Igf2, Nppa, Oxt, Pmch, Prl, Trh

Synaptic vesicle

5

Doc2g, Slc17a6, Syn3, Sv2c, Syt10

Regulation of phosphorylation

6

Cd4, Cd74, Cdk5rap1, Fkbp1a, Irak2, Prkcd

Membrane-bounded vesicle

8

Capn11, Doc2g, Gpnmb, Prl, Slc17a6, Syn3, Sv2c, Syt10

Striated muscle tissue development

4

Fkbp1a, Foxp1, Rxrg, Tnnt2

Blood circulation

4

Acta2, Ace, Avp, Nppa

Lymphocyte activation

4

Cd4, Cd74, Fkbp1a, Foxp1

C2 calcium-dependent membrane targeting

4

Cpne1, Doc2g, Prkcd, Syt10

Immune effector process

4

Cd74, C1qb, Foxp1, Prkcd

Synapse

5

Shc4, Slc17a6, Syn3, Sv2c, Syt10

  1. Cluster name, number of genes within each cluster and acronym of each gene are indicated