Fig. 5From: Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucomaOcular hypertensive rat eyes exhibit early inner plexiform layer synapse loss which is absent in C1 inhibitor treated eyes. Administration of a commercial FDA approved C1 inhibitor reduced synapse loss. a Representative images of rat retinas labelled with PSD-95 to show synapses. b Analysis of synaptic density. NT = normotensive eyes, sham control, OHT = ocular hypertensive eyes. Scale bar = 50 μm, * = P < 0.05, *** = P < 0.001, GCL = ganglion cell layer, IPL = inner plexiform layer, INL = inner nuclear layerBack to article page