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Fig. 13 | Molecular Neurodegeneration

Fig. 13

From: In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells

Fig. 13

The 7-day administration of SP600125 protected I/R-induced reduction in VGLUT2 and PSD95 expression in the superior colliculus. (a) Mouse brains from 7-day SP600125 treatment (15 mg/kg) were collected for immunohistochemistry 28 days post retinal I/R injury. (b) Data represent mean ± SEM (n = 4) of percentages at each hemisphere from both contralateral (dark bars) and ipsilateral (open bars) sides compared to vehicle ipsilalateral volume, set as a 100 %. No significant difference was detected between contralateral and ipsilateral samples by two-tailed, paired Student’s t-test

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Molecular Neurodegeneration

ISSN: 1750-1326