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Fig. 8 | Molecular Neurodegeneration

Fig. 8

From: In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells

Fig. 8

SP600125 protected against I/R-induced cell loss in the GCL. Total cell numbers in the GCL were counted from retinas of vehicle or SP600125-treated animals at 28 days after I/R injury. Non-injured contralateral eyes were also analyzed for comparison. I/R injury induced significant GCL cell loss (30.0 ± 5.6 %) compared to contralateral non-injured eyes whereas SP600125 administration showed total protection. Data represent mean ± SEM (n = 5). *: p < 0.05; NS: non-significant between contralateral control and I/R eyes by two-tailed, paired Student’s t-test

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Molecular Neurodegeneration

ISSN: 1750-1326