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Table 6 Gene-based analyses for Mendelian and GWAS PD genes

From: Resequencing analysis of five Mendelian genes and the top genes from genome-wide association studies in Parkinson’s Disease

Gene cMAF PD cases cMAF controls P OR
GBA 0.084 0.034 0.0007 2.28 (1.41–3.68)
LRRK2 0.069 0.034 0.01 1.86 (1.14–3.02)
DJ-1 0.001 0 0.64 2.1 (0.08–52.1)
PARKIN 0.014 0.012 0.96 1.01 (0.43–2.40)
PINK1 0.006 0.005 0.93 1.05 (0.29–3.77)
MAPT 0.005 0.004 0.82 1.17 (0.27–4.95)
  1. Results of SKAT-O analyses including all the validated coding variants were presented. cMAF = cummulative MAF