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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: Apolipoprotein E lipoprotein particles inhibit amyloid-β uptake through cell surface heparan sulphate proteoglycan

Fig. 1

Characterization of astrocyte-secreted apoE particles. Immunoaffinity purified apoE3 (500 ng) and apoE4 particles (500 ng) were analyzed by non-denaturing gradient gel electrophoresis (4–20 %) (a) and SDS-PAGE (b) followed by Western blot for apoE. Numbers on the left are molecular size markers expressed in kDa. c Total cholesterol concentrations of apoE3 and apoE4 particles were measured using the Amplex Red cholesterol assay kit and normalized against apoE concentrations. Data represent mean ± S.D. (n = 3). ***, p < 0.001

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Molecular Neurodegeneration

ISSN: 1750-1326