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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Apolipoprotein E lipoprotein particles inhibit amyloid-β uptake through cell surface heparan sulphate proteoglycan

Fig. 3

ApoE particles inhibit Aβ cellular uptake through HSPG in CHO cells. CHO-K1 (wild-type) cells or CHO-M1 (HS-deficient) cells were incubated with 50 nM Aβ40 (a) or 50 nM Aβ42 (b) in the presence or absence of apoE3 particle (200 nM) or apoE4 particle (200 nM) for 18 h at 37 °C. The amount of internalized Aβ was quantified by ELISA. Data represent mean ± S.D. (n = 3). **, p < 0.01

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Molecular Neurodegeneration

ISSN: 1750-1326