Fig. 5From: Apolipoprotein E lipoprotein particles inhibit amyloid-β uptake through cell surface heparan sulphate proteoglycanApoE particles suppress Aβ binding to HSPG on the cell surface. CHO-K1 or CHO-M1 cells were incubated with Aβ42 (50 nM) with or without apoE3 particles (200 nM) or apoE4 particles (200 nM) for 3 h at 4 °C. Cell-bound Aβ42 was quantified by ELISA. Data represent mean ± S.D. (n = 3). *, p < 0.05Back to article page