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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Early-life stress leads to impaired spatial learning and memory in middle-aged ApoE4-TR mice

Fig. 5

Decreased GABAergic neurons in the hippocampus of 12-month-old ApoE4-TR mice that underwent early-life CUMS intervention. Immunohistochemical staining of anti-GABA in the hippocampus of ApoE-TR mice at 3 months and 12 months. The dark brown dots represent the anti-GABA -positive GABAergic neurons. Magnified areas indicated by boxes. N = 6 per group, expressed as mean ± SEM. one-factor ANOVA of statistical methods was used. &&& p < 0.001, ### p < 0.001, ***p < 0.001. Scale bars are 200 um

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