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Fig. 9 | Molecular Neurodegeneration

Fig. 9

From: Early-life stress leads to impaired spatial learning and memory in middle-aged ApoE4-TR mice

Fig. 9

Decreased expression of Reelin-Fyn-NMDAR2B in the prefrontal cortex and hippocampus of 12-month-old ApoE4-TR mice that underwent early-life CUMS intervention. The levels of Reelin (170Kd), ApoE, ApoER2, PSD95, SYN, Fyn, p-NR2B, NR2B, p-CREB and CREB were detected respectively by Western blot in the prefrontal cortex and hippocampus. N = 6 per group, expressed as mean ± SEM. one-factor ANOVA was used to analysis the data. *p < 0.05, **p < 0.01, ***p < 0.001, # p < 0.05, ## p < 0.01, ### p < 0.001

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