Table 2 Myeloid-specific ikkβ gene deletion regulates the percentages of CD4⁺, CD4⁺/IFN-γ⁺, CD4⁺/IL-17⁺, and CD4⁺/CD25⁺/Foxp3⁺ T cells

Spinal cord

Wild type

LysM-Cre/Ikkβ^F/F

Wild type

LysM-Cre/Ikkβ^F/F

CD4⁺

0.52 ± 0.17

0.65 ± 0.21

14.47 ± 1.21^##

8.18 ± 0.53^**

CD8⁺

2.53 ± 1.38

2.89 ± 0.13

3.07 ± 0.74

2.76 ± 0.06

CD4⁺/IFN-γ⁺

2.97 ± 0.04

2.98 ± 0.95

11.33 ± 0.69^##

6.34 ± 0.22^**

CD4⁺/IL-17⁺

3.84 ± 0.94

3.01 ± 0.12

14.35 ± 1.21^##

5.43 ± 0.63^**

CD4⁺/IL-4⁺

0.41 ± 0.09

0.49 ± 0.29

0.87 ± 0.13

0.94 ± 0.27

CD4⁺/Foxp3⁺

0.31 ± 0.45

0.37 ± 0.57

4.59 ± 1.97^#

13.49 ± 3.21^*

CD4⁺/CD25⁺/Foxp3⁺

0.46 ± 0.06

0.74 ± 0.10

1.55 ± 0.15^##

4.05 ± 0.80^*

B

Lymph node

Wild type

LysM-Cre/Ikkβ ^F/F

Wild type

LysM-Cre/Ikkβ ^F/F

CD4⁺

8.43 ± 0.64

8.13 ± 0.84

27.77 ± 2.33^##

19.96 ± 2.96^*

CD8⁺

4.85 ± 0.00

4.39 ± 0.10

4.71 ± 1.08

4.06 ± 0.72

CD4⁺/IFN-γ⁺

1.01 ± 0.09

1.24 ± 0.01

9.40 ± 1.98^##

4.59 ± 0.72^*

CD4⁺/IL-17⁺

0.13 ± 0.53

0.10 ± 0.34

14.76 ± 2.64^##

4.13 ± 0.66^**

CD4⁺/IL-4⁺

4.55 ± 0.60

4.29 ± 0.52

3.49 ± 1.32^##

4.01 ± 0.94

CD4⁺/Foxp3⁺

16.49 ± 1.02

15.21 ± 0.37

8.01 ± 1.31^#

11.31 ± 0.20^*

CD4⁺/CD25⁺/Foxp3⁺

5.00 ± 0.21

4.96 ± 0.57

2.75 ± 0.01^##

4.41 ± 0.13^**