Pim1 inhibition as a novel therapeutic strategy for Alzheimer’s disease

Table 1 Descriptive information of patients whose brain tissue was utilized to measure pPRAS40 levels. Gel order indicates the order in which protein samples were loaded in Fig. 1

Age at death	Diagnosis	MMSE score	Braak stage	Gel load order
86	AD	16	IV	1
82	AD	23	IV	2
93	CTL	30	I	3
89	CTL	29	II	4
92	CTL	26	III	5
79	CTL	29	II	6
82	AD	19	V	7
78	AD	0	VI	8
87	CTL	28	III	9
91	CTL	27	II	10
87	CTL	26	III	11
75	CTL	29	III	12
95	CTL	26	III	13
88	AD	9	VI	14
78	AD	-	IV	15
68	AD	0	VI	16
78	CTL	29	III	17
85	AD	23	VI	18
86	AD	20	IV	19

ISSN: 1750-1326

Age at death	Diagnosis	MMSE score	Braak stage	Gel load order
86	AD	16	IV	1
82	AD	23	IV	2
93	CTL	30	I	3
89	CTL	29	II	4
92	CTL	26	III	5
79	CTL	29	II	6
82	AD	19	V	7
78	AD	0	VI	8
87	CTL	28	III	9
91	CTL	27	II	10
87	CTL	26	III	11
75	CTL	29	III	12
95	CTL	26	III	13
88	AD	9	VI	14
78	AD	-	IV	15
68	AD	0	VI	16
78	CTL	29	III	17
85	AD	23	VI	18
86	AD	20	IV	19

Age at death	Diagnosis	MMSE score	Braak stage	Gel load order
86	AD	16	IV	1
82	AD	23	IV	2
93	CTL	30	I	3
89	CTL	29	II	4
92	CTL	26	III	5
79	CTL	29	II	6
82	AD	19	V	7
78	AD	0	VI	8
87	CTL	28	III	9
91	CTL	27	II	10
87	CTL	26	III	11
75	CTL	29	III	12
95	CTL	26	III	13
88	AD	9	VI	14
78	AD	-	IV	15
68	AD	0	VI	16
78	CTL	29	III	17
85	AD	23	VI	18
86	AD	20	IV	19

Age at death	Diagnosis	MMSE score	Braak stage	Gel load order
86	AD	16	IV	1
82	AD	23	IV	2
93	CTL	30	I	3
89	CTL	29	II	4
92	CTL	26	III	5
79	CTL	29	II	6
82	AD	19	V	7
78	AD	0	VI	8
87	CTL	28	III	9
91	CTL	27	II	10
87	CTL	26	III	11
75	CTL	29	III	12
95	CTL	26	III	13
88	AD	9	VI	14
78	AD	-	IV	15
68	AD	0	VI	16
78	CTL	29	III	17
85	AD	23	VI	18
86	AD	20	IV	19