Fig. 6

Experimental variability and occurrence of random efficacy readout in drug trials: Dexpramipexole study. In replicate 1 both riluzole and dexpramipexole (both 10 μM) showed a significant reduction in DsRed fluorescence. However in replicate 2 and 3 only riluzole showed a significant reduction in fluorescence. This highlights the need for stringent assay QC and experimental replicates. N= >10 for each replicate, error bars show SD