Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

Table 2 Summary of BIN1 expression in the brain analysed using cellular markers

Markers Brain tissue	Neurons	Mature	Immature	Microglia	Astrocytes	Macrophages
	Neurons	Oligodendrocytes		Microglia	Astrocytes	Macrophages
	NeuN, Amph 1, Calbindin, Parvalbumin	ASPA, TPP25, CNPase, CC1	NG2	Iba1, CD45	GFAP	CD68
Mouse/rat	−	++++	−	−	−	−
Human	−	++++	ND	−	−	−

The cellular markers employed to determine BIN1 expression in different cell types are indicated. ++++ = strong expression; − = no expression; +/− weak or occasional expression; ND not determined

ISSN: 1750-1326