Treatment | Weeks post-injection | Linear regression | Htt (4,7) % | Linear regression | Atn1 (3,10) % | Linear regression | Atxn2 (6,10) % | Linear regression | Tbp (3,13) % |
---|---|---|---|---|---|---|---|---|---|
ZF-KOX1 | 2 | R 2 = 0.97 § | 92.1 ± 0.4* | R 2 = 0.03 | 101.2 ± 13.8 | R 2 = 0.09 | 95.5 ± 3.9 | R 2 = 0.98 § | 94.5 ± 5.0 |
4 | R 2 = 0.99 § | 89.6 ± 2.4* | R 2 = 0.64 | 91.7 ± 13.7 | R 2 = 0.57 | 96.1 ± 6.8 | R 2 = 0.98 | 91.5 ± 1.7 | |
6 | R 2 = 0.99* | 90.6 ± 9.6 | R 2 = 0.09 | 106.3 ± 4.9 | R 2 = 0.96 | 98.4 ± 2.9 | R 2 = 0.65 | 98.1 ± 3.3 | |
mZF-KRAB | 2 | R 2 = 0.53 | 98.3 ± 3.3 | R 2 = 0.02 | 109.4 ± 10.6 | R 2 = 0.00 | 103.3 ± 11.8 | R 2 = 0.08 | 99.1 ± 7.9 |
4 | R 2 = 0.14 | 88.4 ± 6.7 | R 2 = 0.19 | 88.6 ± 7.3 | R 2 = 0.36 | 89.6 ± 5.4 | R 2 = 0.43 | 90.5 ± 10.4 | |
6 | R 2 = 0.43 | 92.5 ± 11.35 | R 2 = 0.16 | 91.4 ± 6.5 | R 2 = 0.00 | 96.7 ± 4.4 | R 2 = 0.07 | 94.7 ± 4.8 |