Table 1 Clinical, demographic data and classic CSF biomarker levels

yNC

{yNC member of the same ADAD families}

45 ± 2 [25–60]

{37 ± 3 [25–47]}

n = 23 (15 F/8 M)

{6 F/2 M}

29 ± 1 [25–30]

{29 ± 1 [28–30]}

809 ± 44

{791 ± 84}

207 ± 15

{231 ± 29}

43 ± 3

{45 ± 11}

syADAD

45 ± 3 [31–59]

n = 8 (5 F/3 M)

21 ± 2* [11–28]

300 ± 54*

899 ± 186*

164 ± 60*

psADAD

36 ± 3 [24–41]

n = 6 (4 F/2 M)

30 ± 1 [29, 30]

1120 ± 252

222 ± 26

49 ± 5

dDS

55 ± 2 [43–61]

n = 10 (5 F/5 M)

ND

411 ± 24*

788 ± 125*^,a

106 ± 14*^,a

ndDS

43 ± 2 [33–49]

n = 10 (5 F/5 M)

ND

570 ± 51*

232 ± 53

45 ± 8

eNC

67 ± 1 [61–80]

n = 17 (11 F/6 M)

29 ± 1 [26–30]

753 ± 30

197 ± 12

42 ± 2

sAD

68 ± 2 [54–83]

n = 13 (9 F/4 M)

20 ± 1** [18–24]

351 ± 17**

833 ± 87**

135 ± 18**

MCI due to AD

66 ± 1 [61–72]

n = 12 (5 F/7 M

26 ± 1** [20–30]

422 ± 31

618 ± 66**

81 ± 8**