Fig. 3
From: Spinal cord injury induces astroglial conversion towards neuronal lineage
Transdifferentiation of local mature astrocytes into neuronal progenitors after SCI. Experimental time line for BrdU incorporation into newly formed astrocytes (a). Confocal mosaic micrograph showing the lesion site and reference frames for displayed fields of view in C and G (b). Confocal micrographs confirming BrdU incorporation into newly proliferated astroglia (arrows in c, d, f & g) but not in transdifferentiated astrocytes (arrowheads in d, e & g) in Aldh1l1-EGFP mice 2 weeks after HS. Scale bars (b): 100 μm, (c): 50 μm and (d–g): 20 μm. b–g HS 2 weeks