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Fig. 2 | Molecular Neurodegeneration

Fig. 2

From: Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation

Fig. 2

Distribution of CSF apoE4 around arteries but not veins (a) Schematic diagram showing the intracisternal injection site. b-d Representative images of apoE4-647 (red) and dextran-cascade blue (CB) radial distribution at 10, 25 and 50 min post-intracisternal injection. Scale bar = 100 μm. e Distribution distance of apoE4 and CB at different post-injection times. f ApoE4 distribution distance standardized as a percentage of that of CB. Values are mean ± SEM. N = 4. The vasculature was outlined by intravascular labeling with lectin (green)

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